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Nodzynski’s team described the structure of PIN1 hydrophilic loop
Veronika Bilanovicova, Tomasz Nodzynski and his team described the structure of the hydrophilic loop (HL), a central part of PIN1 protein, that serves as a transporter of auxin phytohormone. The research team showed that the hydrophilic loop is an intrinsically disordered protein (IDP). The findings were recently published in the International Journal of Molecular Sciences and will most probably influence the…
VAN4 encodes a putative TRS120 that is required for normal cell growth and vein development in Arabidopsis.
Naramoto S, Nodzyński T, Dainobu T, Takatsuka H, Okada T, Friml J, Fukuda H.Plant Cell Physiol. 2014 Apr;55(4):750-63. doi: 10.1093/pcp/pcu012. Epub 2014 Jan 18.PMID: 24443495 (hard to find due to diacritics)
PIN5 and PIN8 the Yin and Yang of membrane topology
“Mapping the membrane orientation of auxin homeostasis regulators PIN5 and PIN8 in Arabidopsis thaliana root cells reveals their divergent topology” is on-line (and in pdf). Big congratulations to Yewubnesh and the team Vendula, Nikola, Veronika, Marta and Marek. We are very happy to contribute to the very active research field of Endoplasmic Reticulum PIN auxin…
The Hydrophilic Loop of Arabidopsis PIN1 Auxin Efflux Carrier Harbors Hallmarks of an Intrinsically Disordered Protein.
Bilanovičová, V.; Rýdza, N.; Koczka, L.; Hess, M.; Feraru, E.; Friml, J.; Nodzyński, T. International Journal of Molecular Sciences 2022, 23 (11), 6352. https://doi.org/10.3390/ijms23116352
Arabidopsis flippase ALA3 is required for adjustment of early subcellular trafficking in plant response to osmotic stress
Vendula Pukyšová, Adrià Sans Sánchez, Jiří Rudolf, Tomasz Nodzyński, Marta Zwiewka. Journal of Experimental Botany, Volume 74, Issue 17, 13 September 2023, Pages 4959–4977. https://doi.org/10.1093/jxb/erad234 Fantastic work of Venda, Adria, Jiri and Marta. This is an extension of earlier work published in Molecular Plant 2015 showing that subcellular trafficking responds osmotic potential changes. Beside spearheading this osmotic-adaptation focused research…
How Roots Grow Downwards: Mystery of Lipid Asymmetry Influencing Plasma Membrane Protein Delivery Was Uncovered
Members of the Tomasz Nodzynski Research Group from CEITEC Masaryk University contributed to the recent work of Jiri Friml from IST Austria, which was published in Plant Cell, and links intracellular trafficking and auxin coordinated root gravitropism. Gravitropism is the capacity of a plant to sense gravity and align its growth accordingly. The growth of roots along the gravity vector…

